Carnitine is an amino acid which helps in the transport of fatty acids into the mitochondria in your cells where they are broken down and turned into energy. The mitochondria are your cells power sources. Carnitine deficiency is a metabolic state in which carnitine concentrations in your plasma and tissues are less than the levels required for normal function of your body.
Therefore, if you do not have enough carnitine present in your system, your body will not be able to use up fatty acids causing them to build up, and causing you to immediately feel weak after only a little exercise. This carnitine deficiency also leads to hypoketosis, fatty liver, muscle aches and myopathy. Myopathy is a neuromuscular disease in which your muscle fibers do not function properly.
Carnitine deficiency is much more serious in infants. This is because tissue and cell growth is rapid and the demand for energy utilization and tissue accretion leads to depletion of carnitine faster than it can be synthesized. The result can be arrhythmias and even death.
There are two general kinds of carnitine deficiency. They are:
- Primary – This is usually a genetic defect. With primary carnitine deficiency your carnitine transporter does not function like it should. It prevents carnitine from being transported into your cells.
- Secondary – This usually happens due to metabolic disorders in the mitochondria of your cells.
Primary carnitine deficiency is classified in two ways. They are:
- Systemic carnitine deficiency – This affects many of your organ systems including your brain and heart.
- Muscle carnitine deficiency – This is limited to your voluntary muscles.
Secondary carnitine deficiency results as a secondary condition from metabolic disorders in the mitochondria of your cells. Blockage of the metabolic pathways in your mitochondria leads to a build-up of acyl compounds. These compounds then bind to your carnitine and are excreted by your kidneys. This causes your carnitine levels to drop. Some of these mitochondrial disorders include cytochrome c oxidase deficiency, mitochondrial ATPase deficiency, and fatty acyl-CoA dehydrogenase deficiencies.
The effects that you experience with carnitine deficiency are determined by the cause of your condition. Some of the effects are:
- Fatty liver
- Muscle necrosis
- Lipid-storage myopathy
- Hyperammonemia with fatigue, confusion, muscle aches and cardiomyopathy.
You or your child with disability may have carnitine deficiency. This, along with underlying related conditions, may be causing you or your child’s disability.
You may need help. You may need financial help.
You may have applied for Social Security disability benefits from the Social Security Administration because of the disability caused by carnitine deficiency and/or related underlying conditions. Were you or your child with disability denied?
If you are going to appeal the denial by the Social Security Administration, think about this. People with a good disability lawyer like the one at disabilitycasereview.com are approved more often than people without an attorney.
Do not delay. Contact the accomplished disability lawyer at disabilitycasereview.com, today.