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Paraneoplastic Pemphigus Autoimmune Disease and Qualifying For Disability

Pemphigus is an autoimmune disease that is marked by blistering and raw sores on your skin and mucous membranes. The use of Penicillamine is sometimes associated with the occurrence of pemphigus. Penicillamine is a drug that is used in the treatment of rheumatoid arthritis, Wilson’s disease and scleroderma. There are three major types of pemphigus that are vastly different in severity. They are pemphigus vulgaris, pemphigus foliaceus and paraneoplastic pemphigus. Paraneoplastic pemphigus is the rarest kind of pemphigus. However, it is the most serious, severe form of the disease. Most of the time, paraneoplastic pemphigus develops in people who have already been diagnosed with certain types of cancer, such as sarcomas, Castleman‘s disease, non-Hodgkin’s lymphoma, thymoma and chronic lymphocytic leukemia. Paraneoplastic pemphigus affects men and women equally. It usually begins in people who are middle-aged and older, but the disease can also occur in children and young adults. Paraneoplastic pemphigus is evidenced by the binding of antibodies to the surface of the cells of your epidermis, which is the outer layer of your skin. This disease is also marked by conjunctiva (scarring and ulceration of your eye and eyelids), skin lesions that may involve violaceous plaques or blisters and severe ulceration of your lips and mouth. The exact cause of paraneoplastic pemphigus is unknown. As already mentioned, paraneoplastic pemphigus is believed to be an autoimmune disease. An autoimmune disease is one in which for some unknown reason your body’s autoimmune system mistakenly sends antibodies to attack the tissues and cells of your own body. In the case of paraneoplastic pemphigus, there are additional antibodies that are involved in causing the disease that are not seen in other kinds of pemphigus. As mentioned earlier, paraneoplastic pemphigus is almost always connected to a malignancy of some kind. Other signs and symptoms that you may experience include: ?    Skin lesions that are highly variable in what they look like that may develop anywhere on your body ?    These skin lesions may be scaly plaques, ulcerative lesions, red and inflamed spots or fluid-filled blisters ?    Painful sores on your lips and in your mouth ?    Ulceration and scarring of your eye and eyelids (conjunctiva) ?    Lesions in your lungs that may lead to progressive lung disease and make it hard for you to breathe.   You  may have been diagnosed with paraneoplastic pemphigus. Paraneoplastic pemphigus and/or complications that have been brought about by it or other conditions that you have in conjunction with this disease may have resulted in the disability of you or your loved one and be what is causing you not to be able to work.  Paraneoplastic pemphigus may qualify you for SSI or SSDI benefits.
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